Statin-induced bilateral foot drop in a case of hypothyroidism

Muscle involvement is a common manifestation of both clinical and subclinical hypothyroidism, with serum creatine kinase (CK) elevation being probably the most common manifestation, and is seen in seat sleeve up to 90% of patients, but is usually mild (less than 10 times the upper limit of normal).Rhabdomyolysis is a distinctively uncommon presenta

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Chronic pain patients can be classified into four groups: Clustering-based discriminant analysis of psychometric data from 4665 patients referred to a multidisciplinary pain centre (a SQRP study).

To subgroup chronic pain patients using psychometric data and regress the variables most responsible for subgroup discrimination.Cross-sectional, registry-based study.Chronic pain patients assessed at a multidisciplinary pain centre between 2008 and 2015.Data from the Swedish quality registry for pain rehabilitation (SQRP) were retrieved and analys

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Positive Autoregulation of an Acyl-Homoserine Lactone Quorum-Sensing Circuit Synchronizes the Population Response

ABSTRACT Many proteobacteria utilize acyl-homoserine lactone quorum-sensing signals.At low population densities, cells produce a basal level of signal, and when sufficient signal has accumulated in the surrounding environment, it binds to its receptor, and quorum-sensing-dependent genes can be activated.A common characteristic of acyl-homoserine la

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